Emergency Vaccination Reduces Mortality by 60%, Study Reveals

Web Editor

July 20, 2025

a woman getting a vaccium from a doctor in a hospital room with a needle in her arm, Évariste Vital

Background on the Importance of Vaccination Efforts

The global health landscape has been continuously challenged by infectious diseases, with some of the deadliest threats including cholera, Ebola, measles, meningitis, and yellow fever. In response to these challenges, international organizations like Gavi have been instrumental in coordinating vaccination efforts to protect vulnerable populations, particularly children in low-income countries.

Key Findings of the Study

A recent study, supported by Gavi and conducted in collaboration with researchers from the Burnet Institute in Australia, has demonstrated the significant impact of emergency vaccination campaigns on reducing mortality and morbidity during infectious disease outbreaks.

  • Mortality Reduction: The study found that emergency vaccination efforts have reduced deaths by nearly 60% over the past 25 years for five major infectious diseases (cholera, Ebola, measles, meningitis, and yellow fever) in low-income countries.
  • Infection Prevention: Alongside mortality reduction, emergency vaccination has prevented a similar number of infections.
  • Economic Benefits: The economic advantages of vaccination efforts are estimated to be in the tens of billions of euros by avoiding deaths and disabilities.

Detailed Analysis of the Study’s Impact

The study, published in BMJ Global Health, analyzed 210 outbreaks of the five infectious diseases across 49 low-income countries between 2000 and 2023. The research confirmed that vaccine deployment during these outbreaks decreased both infections and deaths by approximately 60% for all five diseases.

Some diseases, such as yellow fever and Ebola, saw even more substantial reductions in mortality: 99% and 76%, respectively. Furthermore, emergency vaccination efforts significantly reduced the risk of disease spread during outbreaks.

Addressing the Global Concern of Vaccine Hesitancy

The study comes at a critical time when the World Health Organization (WHO) has raised alarms about the resurgence of vaccine-preventable diseases worldwide due to misinformation and reduced international aid. This research underscores the importance of vaccination efforts as a cost-effective response to the growing threat of disease outbreaks.

Limitations and Future Considerations

While the study provides compelling evidence of vaccination’s positive impact, it acknowledges that the estimated economic benefits may be an understatement. The analysis does not account for the costs associated with responding to outbreaks nor the broader social and macroeconomic consequences of large-scale disease disruptions.

Key Questions and Answers

  • What is the main finding of the study? Emergency vaccination efforts have reduced mortality by nearly 60% and prevented a similar number of infections for five major infectious diseases in low-income countries.
  • What are the economic benefits of vaccination? Vaccination efforts have generated approximately 27 billion euros in benefits by avoiding deaths and disabilities.
  • Why is this study significant? The research highlights the crucial role of vaccination in combating infectious diseases and provides evidence to counter misinformation that has led to a resurgence of vaccine-preventable diseases.