Ozempic and Wegovy Alter Appetite, Impacting U.S. Food Spending and Forecasting Changes in Global Food Demand

Web Editor

February 2, 2026

a woman with a cast on her stomach holding her arm in her other hand and a cast on her hip, Évarist

Introduction to GLP-1 Medications and Their Economic Influence

The expansion of GLP-1 medications, such as Ozempic and Wegovy, is not only transforming appetite regulation but also causing measurable adjustments in household spending on food in the United States. This shift anticipates structural changes in global food demand, with direct implications for the food and restaurant industries, including Mexico.

Study Findings: Impact on U.S. Household Spending

A recent study published in the Journal of Marketing Research documents that adopting GLP-1 medications is associated with significant reductions in U.S. household spending on food, both at supermarkets and restaurants. This pattern could potentially replicate in other markets as usage grows.

  • Reduction in Spending: Households with at least one GLP-1 medication user reduce their grocery spending by 5.3% during the first six months of medication use. In higher-income households, this reduction exceeds 8%.
  • Impact on Out-of-Home Consumption: Spending on fast food, cafeterias, and limited-service establishments decreases by approximately 8%.
  • Product-Specific Adjustments: Ultraprocessed and high-calorie products, such as salty snacks, sweets, industrial bakery items, and cookies, experience the most significant drops. Meanwhile, a few categories show modest increases, including yogurt, fresh fruit, and nutrition bars.

The study’s authors, Sylvia Hristakeva and Jura Liaukonyte from Cornell SC Johnson College of Business, note that these changes persist for at least the first year, though with some moderation as treatment progresses.

Global Implications of the Phenomenon

Although the analysis focuses on the United States, its findings have global implications. The rapid expansion of GLP-1 medications in both developed and emerging economies introduces a new structural variable in food demand, particularly in urban markets and middle- to high-income segments.

In the U.S., the proportion of households with at least one GLP-1 medication user has grown from 11% by the end of 2023 to over 23% by mid-2025. This growth has drawn the attention of analysts and investors, who are beginning to assess its potential impact on complete value chains—from processed food manufacturers to restaurants, supermarkets, and delivery platforms.

Implications for the Mexican Market

For Mexico, a significant consumer of ultraprocessed foods and with a restaurant sector heavily reliant on out-of-home consumption, this trend represents growing attention. Although GLP-1 medication adoption is still less prevalent than in the U.S., its presence is expanding in urban, high-income segments, particularly in private weight management treatments.

  • Potential Market Impact: Similar patterns could affect key Mexican market categories, including snacks, industrial bakery items, sugary beverages, and fast food. This could also influence the average restaurant check size for limited-service establishments.
  • Opportunities in Healthier Segments: The trend might open opportunities in segments associated with perceived healthier foods, individual portions, high-protein products, and lower-consumption formats.
  • Treatment Discontinuation: Approximately one-third of users discontinue treatment, causing food spending to return to previous levels or even slightly less healthy baskets. This suggests that the phenomenon might generate cyclical adjustments in demand, with varying effects across income segments.

The study’s authors caution that it is not possible to entirely separate the medication’s biological effect from other lifestyle changes, but evidence points to appetite suppression as the primary driver of observed spending adjustments. For the food and restaurant industries, this implies facing a scenario where consumption volume—not just price—could become a structural risk factor.

Globally, and particularly in markets like Mexico, the expansion of GLP-1 medications initiates a new discussion on the future of food consumption, product reformulation, portion sizes, and business strategies in an environment where consumer appetite is changing from the ground up.