New H3N2 Influenza Variant in Mexico: Symptoms and Precautions

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December 13, 2025

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Introduction to the H3N2 Influenza Variant

Mexico is currently facing a new variant of the H3N2 influenza virus, which has authorities both nationally and internationally advising caution without causing widespread alarm. The concern lies in the possibility of a more intense winter season, prompting calls to reinforce vaccination efforts and epidemiological surveillance.

Who is Dr. Florence de Jager?

Dr. Florence de Jager, an infectious disease specialist at the National Institute of Medical Sciences and Nutrition Salvador Zubirán (INSM) in Mexico City, is a key figure in addressing this new variant. Her expertise and ongoing research contribute significantly to understanding the implications of H3N2 and guiding public health measures.

Understanding the H3N2 Influenza Variant

H3N2, or influenza type A (H3N2), is a subtype of the influenza virus responsible for seasonal epidemics and occasional pandemics. This variant has been a persistent challenge for global health due to its ability to mutate and evade existing immunity. The new subclade, K, has emerged in Mexico and is under close observation.

Symptoms of H3N2 Influenza

Common symptoms of the H3N2 influenza variant include:

  • Fever
  • Cough
  • Sore throat
  • Runny or stuffy nose
  • Muscle or body aches
  • Headaches
  • Fatigue

Severe Complications

In some cases, H3N2 can lead to severe complications such as pneumonia, acute respiratory distress syndrome (ARDS), and even death, particularly among high-risk groups like the elderly, young children, and individuals with underlying health conditions.

Recommendations for Prevention and Care

Authorities emphasize the importance of taking preventive measures to minimize the impact of this new H3N2 variant:

  1. Vaccination: Get vaccinated against seasonal influenza, as it is the most effective way to prevent infection.
  2. Hygiene Practices: Regularly wash your hands, cover your mouth and nose when coughing or sneezing, and avoid close contact with sick individuals.
  3. Stay Informed: Keep up-to-date with the latest information from health authorities regarding the H3N2 variant and any necessary precautions.
  4. Seek Medical Attention: If you experience severe symptoms or are part of a high-risk group, consult a healthcare professional promptly.

Key Questions and Answers

  • What is the new H3N2 variant in Mexico? The new subclade, K, of the H3N2 influenza virus has emerged in Mexico, prompting heightened vigilance due to its potential for a more intense winter season.
  • Who is Dr. Florence de Jager? Dr. Florence de Jager is an infectious disease specialist at the National Institute of Medical Sciences and Nutrition Salvador Zubirán (INSM) in Mexico City, contributing significantly to understanding and addressing the new H3N2 variant.
  • What are the common symptoms of H3N2 influenza? Common symptoms include fever, cough, sore throat, runny or stuffy nose, muscle or body aches, headaches, and fatigue.
  • Who is at higher risk for severe complications from H3N2? High-risk groups include the elderly, young children, and individuals with underlying health conditions.
  • What preventive measures should I take against H3N2? Get vaccinated, practice good hygiene, stay informed about the latest developments, and seek medical attention if necessary.